Pancreatic cancer

Pepper Therapeutics

Repurposing phenformin as a potential treatment for pancreatic cancer, building on academic research from Amsterdam UMC and Erasmus MC and creating a route towards clinical development.

Amsterdam UMC + Erasmus MC Phenformin Phase I/II planned
Amsterdam UMC
Academic origin
Amsterdam UMC + Erasmus MC
01
Opportunity + development

A known compound.
A new clinical use.

Pepper Therapeutics builds on preclinical research supporting phenformin as a potential treatment for pancreatic cancer.

The programme brings the academic science into a dedicated development structure, with the next step focused on preparing the programme for clinical testing.

Academic
science
Programme
structure
Development
Clinical
progression
Patient
access
02

Pepper Therapeutics

Pancreatic cancer

02
What Orfenix adds

The structure around the science.

03
Access + next step

Designed for development.
Designed for access.

Access by design

Access should not become a question only after approval.

Pepper Therapeutics is being developed with a model intended to balance continued development with responsible future patient access.

01 Socially responsible licensing
02 Cost-based pricing
03 Modest profit margin
NEXT ↗
Planned Phase I/II

Moving towards first clinical testing.

The planned study will assess safety and dosing while generating preliminary evidence of efficacy.

Built with Amsterdam UMC Erasmus MC Support Casper Foundation RARE-NL